A life-threatening Allergy, coming into contact with the irritant specified is likely to kill a character with this Weakness.

This character's AI hates him and seeks to harm the character.

The unfortunate individual with this potent Weakness is carrying an explosive device on the inside.  Not easily detectable by standard diagnotic tools and likely (99%) to detonate if tampered with, this device may be remotely activated by an outside agency.  This is essentially a lethal leash.

There is something wrong with the design or implementation of the artificial systems of a character with this Weakness and they will tend to fail, sometimes dramatically.

Devourers are condemned to consume the life force of other beings in order to survive.

Sometimes the onboard AI is so potent, it completely subsumes the personality of its host.  While not necessarily life-threatening, the often unusual "thought processes" of AI's make this situation apparent to anyone with experience in dealing with Artificial Intellgences.

A Faulty AI is somehow damaged.  It will show a strong tendency to behave in unpredictable ways.  For the character with this Weakness, it would be very much like sharing one's skull with a raving lunatic.

Due to physiology, specific mutation, or design, a Fragile character is easily broken and will take maximum physical damage from all sources.

A Haunted character is pursued by the ghosts of the fallen.  While mental illnesses may manifest a similar persecution complex, this Weakness is the real thing.

This character is emotionally dead.

Despite any evidence to the contrary, a Monstrous character is treated as an otherworldly being by the bulk of her own species.  Not necessarily frightening in and of themselves, Monstrous characters deviate so far from "normal" as to often inspire at least curiosity if not awe or horror.

A character with the Obsolete Weakness has great difficulty finding spare parts.

The energy that emanates from Radioactive characters is harmful to organic life.

This character's artificial systems differ enough from known technologies as to make the character dependant upon the original engineer.  Attempts at repair and retrofitting are made at greatly enhanced difficulty and spare parts are nonexistant save from the original engineer.

Whether this speaks to artificial systems possessed by a character or that character's own physiology, there is a fair chance that the character may explode.

Individuals burdened with this Weakness have Powers (and corresponding Weaknesses) that are in constant flux.

This character is doomed.  With the passage of time, a Wasting character will eventually cease to be.

This character's artificial systems are especially vulnerable to outside electromagnetic interference.